AG-1288

Catalog No. A13587

AG-1288 is a tyrosine kinase inhibitor. Has been shown in human amnion cells (IC50 =21 mM) to block glucocorticoid-induced cytotoxicity, TNFα-induced cytotoxicity, and glucocorticoid-induced COX-2 activity.
Catalog Num A13587
M. Wt 231.2
Formula C10H5N3O4
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 116313-73-6
Synonyms AG1288, AG 1288, Tyrphostin AG 1288
SMILES C1=C(C=C(C(=C1[N+](=O)[O-])O)O)C=C(C#N)C#N
AG-1288 is a tyrosine kinase inhibitor. Has been shown in human amnion cells (IC50 =21 mM) to block glucocorticoid-induced cytotoxicity, TNFα-induced cytotoxicity, and glucocorticoid-induced COX-2 activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 43.25 mL 216.26 mL 432.53 mL
0.5 mM 8.65 mL 43.25 mL 86.51 mL
1 mM 4.33 mL 21.63 mL 43.25 mL
5 mM 0.87 mL 4.33 mL 8.65 mL

*The above data is based on the productmolecular weight 231.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.