AR-231453Catalog No. A13716

Quick Overview

AR-231453 is a potent and selective small molecule agonis of GPR119 that enhances glucose dependent insulin secretion and glucagon like peptide-1 (GLP-1) release.
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AR-231453

Product Information
Catalog Num A13716
M. Wt 505.5
Formula C21H24FN7O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 733750-99-7
Synonyms AR231453, AR 231453
Chemical Name 2-Fluoro-4-methanesulfonyl-phenyl)-{6-[4-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-yl]-5-nitro-pyrimidin-4-yl}-amine
SMILES Code CC(C)C1=NOC(=N1)C2CCN(CC2)C3=C(C(=NC=N3)NC4=C(C=C(C=C4)S(=O)(=O)C)F)[N+](=O)[O-]

Biological activity
Introduction
AR-231453 is a potent and selective small molecule agonis of GPR119 that enhances glucose dependent insulin secretion and glucagon like peptide-1 (GLP-1) release.
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