Zearalenone

Catalog No. A13740

Zearalenone is a phytoestrogenic mycotoxin usually produced by Fusarium species, is shown to be a cytotoxic compound, but alos binds to the estrogen receptor (ER) (IC50 values are 166 and 240 nM for ERβ and ERα respectively) and was found to stimulate the transcriptional activity of both subtypes at concentrations between 1 - 10 nM.

Product Citations

Muthulakshmi S, .et al. Mycotoxin zearalenone induced gonadal impairment and altered gene expression in the hypothalamic-pituitary-gonadal axis of adult female zebrafish (Danio rerio), J Appl Toxicol, 2018, Nov;38(11):1388-1397 PMID: 29923290

Technical details

Catalog Num	A13740
M. Wt	318.36
Formula	C18H22O5
Purity	>98%
Storage	at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.	17924-92-4
Synonyms
SMILES	C[C@H]1CCCC(=O)CCC/C=C/C2=CC(=CC(=C2C(=O)O1)O)O

Biological Activity

Solubility *

In vitro	DMSO	56 mg/mL (175.9 mM)
	Water	Insoluble
	Ethanol	56 mg/mL (175.9 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.41 mL	157.05 mL	314.11 mL
0.5 mM	6.28 mL	31.41 mL	62.82 mL
1 mM	3.14 mL	15.71 mL	31.41 mL
5 mM	0.63 mL	3.14 mL	6.28 mL

*The above data is based on the productmolecular weight 318.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.