BMS303141

Catalog No. A13807

BMS303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model.
Catalog Num A13807
M. Wt 424.3
Formula C19H15Cl2NO4S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 943962-47-8
Synonyms BMS 303141, BMS-303141
SMILES COC1=C(C=C(C=C1)C2=CC=CC=C2)NS(=O)(=O)C3=CC(=CC(=C3O)Cl)Cl
BMS303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.57 mL 117.84 mL 235.68 mL
0.5 mM 4.71 mL 23.57 mL 47.14 mL
1 mM 2.36 mL 11.78 mL 23.57 mL
5 mM 0.47 mL 2.36 mL 4.71 mL

*The above data is based on the productmolecular weight 424.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.