BAPTA/AM

Catalog No. A14023

BAPTA/AM, an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures.
  • Shichen Xu, .et al. Capsaicin induces mitochondrial dysfunction and apoptosis in anaplastic thyroid carcinoma cells via TRPV1-mediated mitochondrial calcium overload, Cell Signal, 2020, Aug 6;75:109733 PMID: 32771398
  • Zhang L, .et al. Curcumin induces endoplasmic reticulum stress-associated apoptosis in human papillary thyroid carcinoma BCPAP cells via disruption of intracellular calcium homeostasis, Medicine (Baltimore), 2018, Jun;97(24):e11095 PMID: 29901626
  • Miho Akimoto, .et al. Antidiabetic adiponectin receptor agonist AdipoRon suppresses tumour growth of pancreatic cancer by inducing RIPK1/ERK-dependent necroptosis, Cell Death Dis, 2018, Aug; 9(8): 804 PMID: 30038429
Catalog Num A14023
M. Wt 764.68
Formula C34H40N2O18
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 126150-97-8
Synonyms BAPTA-AM, BAPTA AM
SMILES CC(=O)OCOC(=O)CN(CC(=O)OCOC(=O)C)C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C
BAPTA/AM, an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures.
Targets
In vitro DMSO 19 mg/mL (24.84 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.08 mL 65.39 mL 130.77 mL
0.5 mM 2.62 mL 13.08 mL 26.15 mL
1 mM 1.31 mL 6.54 mL 13.08 mL
5 mM 0.26 mL 1.31 mL 2.62 mL

*The above data is based on the productmolecular weight 764.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.