K02288Catalog No. A14311

Quick Overview

K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6.
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K02288

Product Information
Catalog Num A14311
M. Wt 352.38
Formula C20H20N2O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1431985-92-0
Synonyms K 02288, K-02288
SMILES Code COC1=CC(=CC(=C1OC)OC)C2=C(N=CC(=C2)C3=CC(=CC=C3)O)N

Biological activity
Introduction
K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6.
Targets
Target Value
ALK2IC50: 1.1nM
ALK1IC50: 1.8nM
ALK6IC50: 6.4nM
ALK3IC50: 34.4nM
ALK4IC50: 302nM
ALK5IC50: 321nM
Solubility
Solubility (25C)* In vitro DMSO 70 mg/mL (198.64 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
Adooq Bioscience has Satisfaction Guarantee return policy. You may return/exchange any items within 365 days from the original purchase date if you are not satisfied with your purchase, either for protocol related or product related problems.

>>This offer is only valid for products purchased directly from Adooq and its authorized distributors.

>>Prior to returning any items, please contact the Customer Service ([email protected]com) to obtain an Return/Exchange Authorization. Items returned without prior authorization may not be accepted. Any items returned to Adooq should be in the original packaging and in the same condition as originally purchased.


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High Purity Kinase Inhibitors on Signaling Pathways

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