CEP-32496 hydrochloride

Catalog No. A15040

CEP-32496 hydrochloride is a highly potent inhibitor of wild-type BRAF, V600E mutant BRAF and c-Raf with Kd values of 14 nM, 36 nM and 39 nM, respectively.
Catalog Num A15040
M. Wt 553.92
Formula C24H23ClF3N5O5
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1227678-26-3
Synonyms CEP 32496 hydrochloride, CEP32496 hydrochloride
SMILES CC(C)(C1=CC(=NO1)NC(=O)NC2=CC(=CC=C2)OC3=NC=NC4=CC(=C(C=C43)OC)OC)C(F)(F)F.Cl
CEP-32496 hydrochloride is a highly potent inhibitor of wild-type BRAF, V600E mutant BRAF and c-Raf with Kd values of 14 nM, 36 nM and 39 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.05 mL 90.27 mL 180.53 mL
0.5 mM 3.61 mL 18.05 mL 36.11 mL
1 mM 1.81 mL 9.03 mL 18.05 mL
5 mM 0.36 mL 1.81 mL 3.61 mL

*The above data is based on the productmolecular weight 553.92. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.