Eltrombopag Olamine

Catalog No. A15078

Eltrombopag olamine is a new, orally active thrombopoietin-receptor (c-mpl) agonist that stimulates thrombopoiesis.

Technical details

Catalog Num	A15078
M. Wt	564.63
Formula	C29H36N6O6
Purity	>98%
Storage	at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.	496775-62-3
Synonyms	Eltrombopag diethanolamine salt, Promacta, Revolade, SB-497115GR
SMILES	CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)NN=C3C=CC=C(C3=O)C4=CC(=CC=C4)C(=O)O)C.C(CO)N.C(CO)N

Biological Activity

Eltrombopag olamine is a new, orally active thrombopoietin-receptor (c-mpl) agonist that stimulates thrombopoiesis.

Targets

thrombopoietin receptor

Solubility *

In vitro	DMSO	85 mg/mL (150.54 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.71 mL	88.55 mL	177.11 mL
0.5 mM	3.54 mL	17.71 mL	35.42 mL
1 mM	1.77 mL	8.86 mL	17.71 mL
5 mM	0.35 mL	1.77 mL	3.54 mL

*The above data is based on the productmolecular weight 564.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.