Epacadostat (INCB024360)

Catalog No. A15554

Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM, Phase 2,
Catalog Num A15554
M. Wt 438.23
Formula C11H13BrFN7O4S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1204669-58-8, 1204669-37-3
Synonyms INCB 024360
SMILES C1=CC(=C(C=C1NC(=C2C(=NON2)NCCNS(=O)(=O)N)N=O)Br)F
Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM, Phase 2,
Targets
IDO1
10 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.82 mL 114.1 mL 228.19 mL
0.5 mM 4.56 mL 22.82 mL 45.64 mL
1 mM 2.28 mL 11.41 mL 22.82 mL
5 mM 0.46 mL 2.28 mL 4.56 mL

*The above data is based on the productmolecular weight 438.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.