AZD6738 (Ceralasertib)

Catalog No. A15794

AZD6738 is a potent inhibitor of ATR kinase activity with an IC50 of 1 nM against the isolated enzyme and 74 nM against ATR kinase-dependent CHK1 phosphorylation in cells.
Catalog Num A15794
M. Wt 412.51
Formula C20H24N6O2S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1352226-88-0
Synonyms AZD-6738, AZD 6738
SMILES C[[email protected]]1N(C2=NC(C3=C4C(NC=C4)=NC=C3)=NC(C5([[email protected]](=O)(C)=N)CC5)=C2)CCOC1
AZD6738 is a potent inhibitor of ATR kinase activity with an IC50 of 1 nM against the isolated enzyme and 74 nM against ATR kinase-dependent CHK1 phosphorylation in cells.
Targets
ATR
1 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.24 mL 121.21 mL 242.42 mL
0.5 mM 4.85 mL 24.24 mL 48.48 mL
1 mM 2.42 mL 12.12 mL 24.24 mL
5 mM 0.48 mL 2.42 mL 4.85 mL

*The above data is based on the productmolecular weight 412.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.