PRI-724

Catalog No. A15856

PRI-724, an isomer or enantiomer of ICG-001 (A11039), is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity.

Catalog Num A15856
M. Wt 548.24
Formula C33H32N4O4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 847591-62-2
Synonyms PRI 724, PRI724
SMILES O=C(N(CC1)[[email protected]](CN(CC2=C3C=CC=CC3=CC=C2)C([[email protected]@H]4CC5=CC=C(O)C=C5)=O)([H])N4C1=O)NCC6=CC=CC=C6

PRI-724, an isomer or enantiomer of ICG-001 (A11039), is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity.

Targets
Wnt/β-catenin
150 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.24 mL 91.2 mL 182.4 mL
0.5 mM 3.65 mL 18.24 mL 36.48 mL
1 mM 1.82 mL 9.12 mL 18.24 mL
5 mM 0.36 mL 1.82 mL 3.65 mL

*The above data is based on the productmolecular weight 548.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.