L-685458

Catalog No. A15899

L-685458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.
Catalog Num A15899
M. Wt 672.85
Formula C39H52N4O6
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 292632-98-5
Synonyms L685458, L 685458, L685,458
SMILES O=C(OC(C)(C)C)N[[email protected]]([[email protected]](O)C[[email protected]@H](CC1=CC=CC=C1)C(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](CC2=CC=CC=C2)C(N)=O)=O)=O)CC3=CC=CC=C3
L-685458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.
Targets
Gamma-secretase
17 nM(Ki)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.86 mL 74.31 mL 148.62 mL
0.5 mM 2.97 mL 14.86 mL 29.72 mL
1 mM 1.49 mL 7.43 mL 14.86 mL
5 mM 0.3 mL 1.49 mL 2.97 mL

*The above data is based on the productmolecular weight 672.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.