CHZ868

Catalog No. A15937

CHZ868 is a potent and selective type II JAK inhibitor which demonstrates activity in JAK inhibitor persistent cells, murine MPN models, and MPN patient samples.
Catalog Num A15937
M. Wt 423.42
Formula C22H19F2N5O2
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 1895895-38-1
Synonyms CHZ 868, CHZ-868
SMILES CC(NC1=NC=CC(OC2=CC=C3N(C)C(NC4=CC=C(F)C=C4F)=NC3=C2C)=C1)=O
CHZ868 is a potent and selective type II JAK inhibitor which demonstrates activity in JAK inhibitor persistent cells, murine MPN models, and MPN patient samples.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.62 mL 118.09 mL 236.17 mL
0.5 mM 4.72 mL 23.62 mL 47.23 mL
1 mM 2.36 mL 11.81 mL 23.62 mL
5 mM 0.47 mL 2.36 mL 4.72 mL

*The above data is based on the productmolecular weight 423.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.