GNF-6231

Catalog No. A16849

GNF-6231 is a potent, orally active and selective Porcupine inhibitor with IC50 of 0.8 nM.
Catalog Num A16849
M. Wt 448.49
Formula C24H25FN6O2
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 1243245-18-2
Synonyms GNF6231, GNF 6231
SMILES O=C(NC1=NC=C(N2CCN(C(C)=O)CC2)C=C1)CC3=CN=C(C4=CC(F)=NC=C4)C(C)=C3
GNF-6231 is a potent, orally active and selective Porcupine inhibitor with IC50 of 0.8 nM.
In vitro DMSO 87 mg/mL (193.98 mM)
Water Insoluble
Ethanol 5 mg/mL (11.14 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.3 mL 111.49 mL 222.97 mL
0.5 mM 4.46 mL 22.3 mL 44.59 mL
1 mM 2.23 mL 11.15 mL 22.3 mL
5 mM 0.45 mL 2.23 mL 4.46 mL

*The above data is based on the productmolecular weight 448.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.