DC661

Catalog No. A17236

DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor. DC661 inhibits autophagy. DC661 is capable of deacidifying the lysosome and inhibiting autophagy significantly better than hydroxychloroquine (HCQ).
Catalog Num A17236
M. Wt 552.588
Formula C31H39Cl2N5
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 1872387-43-3
Synonyms DC-661; DC 661;
SMILES CN(CCCCCCNC1=CC=NC2=CC(Cl)=CC=C12)CCCCCCNC3=CC=NC4=CC(Cl)=CC=C34
DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor. DC661 inhibits autophagy. DC661 is capable of deacidifying the lysosome and inhibiting autophagy significantly better than hydroxychloroquine (HCQ).
In vitro DMSO 55 mg/mL (99.53 mM)
Water Insoluble
Ethanol 44 mg/mL (79.62 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.1 mL 90.48 mL 180.97 mL
0.5 mM 3.62 mL 18.1 mL 36.19 mL
1 mM 1.81 mL 9.05 mL 18.1 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 552.588. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.