Defactinib hydrochloride

Catalog No. A22003

Defactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.
Catalog Num A22003
M. Wt 546.95
Formula C20H22ClF3N8O3S
Purity >98%
Storage at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No. 1073160-26-5
Synonyms VS-6063 hydrochloride, VS6063, VS 6063; PF 04554878 hydrochloride, PF-04554878, PF04554878
SMILES O=C(NC)C1=CC=C(NC2=NC=C(C(F)(F)F)C(NCC3=NC=CN=C3N(C)S(=O)(C)=O)=N2)C=C1.[H]Cl
Defactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.28 mL 91.42 mL 182.83 mL
0.5 mM 3.66 mL 18.28 mL 36.57 mL
1 mM 1.83 mL 9.14 mL 18.28 mL
5 mM 0.37 mL 1.83 mL 3.66 mL

*The above data is based on the productmolecular weight 546.95. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.