Catalog No.Inhibitor Name Dehydrogenase
A10613Mycophenolate Mofetil
A12899PluriSIn #1 (NSC 14613)
A10070Ammonium Glycyrrhizinate
A14795Gossypol Acetate

1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. Ammonium Glycyrrhizinate (AMGZ)

    Catalog No. A10070
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    Dehydrogenase inhibitor
    Mono-ammonium glycyrrhizinate(AMGZ) is a unique product derived from Licorice root and has an extremely sweet taste. Learn More
  2. Vidofludimus (4SC-101)

    Catalog No. A12997
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    DHODH inhibitor
    Vidofludimus is a novel orally active and potent DHODH inhibitor. Learn More
  3. AZD4017

    Catalog No. A13542
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    HSD1 inhibitor
    AZD4017 is a potent, selective, and orally bioavailable11b-HSD1 inhibitor (11b-hydroxysteroid dehydrogenase type 1 inhibitor). Learn More
  4. MK-8245 Trifluoroacetate

    Catalog No. A15170
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    Liver-targeting SCD Inhibitor‎
    MK-8245 trifluoroacetate is a liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. Learn More
  5. NCT-501

    Catalog No. A15892
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    hALDH1 Inhibitor‎
    NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM. Learn More
  6. AG-120

    Catalog No. A15869
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    Dehydrogenase Inhibitor
    AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Learn More
  7. Fomepizole

    Catalog No. A16164
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    alcohol dehydrogenase inhibitor
    Fomepizole is an alcohol dehydrogenase inhibitor used for the treatment of ethylene glycol and methanol poisonings in adults. Learn More
  8. CGP 3466B maleate

    Catalog No. A12385
    GAPDH inhibitor
    CGP 3466B maleate is an orally active glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor. Learn More
  9. Brequinar

    Catalog No. A12442
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    Dihydroorotate Dehydrogenase Inhibitor
    Brequinar is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis. Learn More
  10. MK-8245

    Catalog No. A11403
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    SCD inhibitor
    MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia. Learn More
  11. Leflunomide

    Catalog No. A10521
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    Dehydrogenase inhibitor
    Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs. Leflunomide is used to relieve symptoms caused by rheumatoid arthritis, such as inflammation, swelling, stiffness, and joint pain. Learn More
  12. CPI-613

    Catalog No. A11786
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    Dehydrogenase Inhibitor
    CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities. Learn More
  13. CBR 5884

    Catalog No. A16176
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    PHGDH inhibitor
    CBR 5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 uM. Learn More

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