ZM 336372

Catalog No.: A11077
C-Raf inhibitor
ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activation of Raf-1 in whole cells.
Grouped product items
Product Name Price Stock Qty
ZM 336372 5mg
$40.00
In stock
ZM 336372 10mg
$70.00
In stock
ZM 336372 50mg
$200.00
In stock
ZM 336372 100mg
$350.00
In stock
ZM 336372 10mM * 1mL in DMSO
$60.00
In stock
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Biological Activity
Discription ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activation of Raf-1 in whole cells.
Targets
Target Value
Product Information
Catalog Num A11077
Formula C23H23N3O3
Molecular Weight 389.5
CAS Number 208260-29-1
SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)N(C)C)NC(=O)C3=CC=C(C=C3)O
Synonyms ZM-336372, ZM336372
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 75 mg/mL (192.58 mM)
Water Insoluble
Ethanol 2 mg/mL (5.13 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.67 mL 128.37 mL 256.74 mL
0.5 mM 5.13 mL 25.67 mL 51.35 mL
1 mM 2.57 mL 12.84 mL 25.67 mL
5 mM 0.51 mL 2.57 mL 5.13 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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