AZD-3965

Catalog No.: A14186
MCT1 inhibitor
AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, is 6 fold selective over MCT2 and does not inhibit MCT4 at 10 μM.
Grouped product items
Product Name Price Stock Qty
AZD-3965 5mg
$120.00
In stock
AZD-3965 10mg
$150.00
In stock
AZD-3965 25mg
$260.00
In stock
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Adooq Products cited in reputable paper
Adooq's AZD-3965 has been cited by 1 publications
  • Lu Gao, .et al. , Int J Biol Sci, 2022, Jan 1;18(2):599-616 PMID: 35002512
  • Biological Activity
    Discription AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, is 6 fold selective over MCT2 and does not inhibit MCT4 at 10 μM.
    Targets
    Target Value
    Product Information
    Catalog Num A14186
    Formula C21H24F3N5O5S
    Molecular Weight 515.5
    CAS Number 1448671-31-5
    SMILES O=C1N(C(C)C)C2=C(C(C(N3OC[C@@](C)(O)C3)=O)=C(CC4=C(C(F)(F)F)NN=C4C)S2)C(N1C)=O
    Synonyms AZD3965,AZD 3965
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 96 mg/mL (186.22 mM)
    Water Insoluble
    Ethanol 96 mg/mL (186.22 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.4 mL 96.99 mL 193.99 mL
    0.5 mM 3.88 mL 19.4 mL 38.8 mL
    1 mM 1.94 mL 9.7 mL 19.4 mL
    5 mM 0.39 mL 1.94 mL 3.88 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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