AMG-925

Catalog No.: A14025
Dual FLT3/CDK4 inhibitor
AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor.
Grouped product items
Product Name Price Stock Qty
AMG-925 5mg
$77.00
In stock
AMG-925 10mg
$120.00
In stock
AMG-925 25mg
$231.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

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Biological Activity
Discription AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor.
Targets
Target Value
Product Information
Catalog Num A14025
Formula C26H29N7O2
Molecular Weight 471.55
CAS Number 1401033-86-0
SMILES CC1CCC(CC1)N2C3=C(C=CN=C3)C4=CN=C(N=C42)NC5=NC6=C(CN(CC6)C(=O)CO)C=C5
Synonyms AMG925, AMG 925
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 0.01 mg/mL (0.02 mM)
Water <1 mg/mL
Ethanol Insoluble
In vivo 2% hydroxypropyl methylcellulose+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.21 mL 106.03 mL 212.07 mL
0.5 mM 4.24 mL 21.21 mL 42.41 mL
1 mM 2.12 mL 10.6 mL 21.21 mL
5 mM 0.42 mL 2.12 mL 4.24 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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