Clozapine

Clozapine displays a broad range of pharmacological actions; the antipsychotic effects are thought to be mediated principally by 5-HT2A/2C and dopamine receptor blockade.
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Product Name Price Stock Qty
Clozapine 500mg
$50.00
In stock
Clozapine 1g
$90.00
In stock
Clozapine 2g
$150.00
In stock
Clozapine 10mM * 1mL in DMSO
$59.00
In stock
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Adooq Products cited in reputable paper
Adooq's Clozapine has been cited by 5 publications
  • Madeleine S A Tan, .et al. , Mol Pharm, 2022, Sep 23 PMID: 36149013
  • Madeleine S. A. Tan, .et al. , Gels, 2022, Jan; 8(1): 38 PMID: 35049572
  • Milan D Valyear, .et al. , Nat Commun, 2020, Jul 28;11(1):3764 PMID: 32724058
  • Yutaro Kobayashi, .et al. , Transl Psychiatry, 2019, 9:181 PMID: 31371697
  • M.D. Valyear, .et al. , bioRxiv, 2018, 2018
  • Biological Activity
    Discription Clozapine displays a broad range of pharmacological actions; the antipsychotic effects are thought to be mediated principally by 5-HT2A/2C and dopamine receptor blockade.
    Targets
    Target Value
    Product Information
    Catalog Num A10236
    Formula C18H19ClN4
    Molecular Weight 326.8
    CAS Number 5786-21-0
    SMILES CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl
    Synonyms Clozaril, Fazaclo, HF 1854, Iprox, Klozapol, Leponex
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 59 mg/mL (180.52 mM)
    Water Insoluble
    Ethanol 29 mg/mL (88.73 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 30.6 mL 153 mL 306 mL
    0.5 mM 6.12 mL 30.6 mL 61.2 mL
    1 mM 3.06 mL 15.3 mL 30.6 mL
    5 mM 0.61 mL 3.06 mL 6.12 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

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