SM-164

Catalog No.: A15800
cIAP-2 antagonist
SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively.
Grouped product items
Product Name Price Stock Qty
SM-164 5mg
$280.00
In stock
SM-164 10mg
$500.00
In stock
SM-164 25mg
$1,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's SM-164 has been cited by 2 publications
  • Hanna Yuk, .et al. , Antioxidants (Basel), 2021, Aug 25;10(9):1347 PMID: 34572979
  • Caroline Moerke, .et al. , Cell Death Differ, 2018, Nov 15 PMID: 30442947
  • Biological Activity
    Discription SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A15800
    Formula C62H84N14O6
    Molecular Weight 1121.42
    CAS Number 957135-43-2
    SMILES CC(C(=O)NC1CCCCC2CCC(N2C1=O)C(=O)NC(C3=CC=CC=C3)C4=CN(N=N4)CCCCC5=CC=C(C=C5)CCCCN6C=C(N=N6)C(C7=CC=CC=C7)NC(=O)C8CCC9N8C(=O)C(CCCC9)NC(=O)C(C)NC)NC
    Synonyms SM 164, SM164
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 3 mg/mL (2.67 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 8.92 mL 44.59 mL 89.17 mL
    0.5 mM 1.78 mL 8.92 mL 17.83 mL
    1 mM 0.89 mL 4.46 mL 8.92 mL
    5 mM 0.18 mL 0.89 mL 1.78 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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