TCS PIM-1 4a (SMI-4a)

Catalog No.: A11967
Pim inhibitor
TCS PIM-1 4a is a selective and ATP-competitive Pim kinase inhibitor (IC50 values = 24 and 100 nM for Pim-1 and Pim-2, respectively).
Grouped product items
Product Name Price Stock Qty
TCS PIM-1 4a 10mg
$65.00
In stock
TCS PIM-1 4a 25mg
$150.00
In stock
TCS PIM-1 4a 50mg
$265.00
In stock
TCS PIM-1 4a 10mM * 1mL in DMSO
$82.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription TCS PIM-1 4a is a selective and ATP-competitive Pim kinase inhibitor (IC50 values = 24 and 100 nM for Pim-1 and Pim-2, respectively).
Targets
Target Value
Product Information
Catalog Num A11967
Formula C11H6F3NO2S
Molecular Weight 273.23
CAS Number 438190-29-5
SMILES O=C(NC/1=O)SC1=C\C2=CC=CC(C(F)(F)F)=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 47 mg/mL (172.01 mM)
Water Insoluble
Ethanol 28 mg/mL (102.47 mM)
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.6 mL 183 mL 365.99 mL
0.5 mM 7.32 mL 36.6 mL 73.2 mL
1 mM 3.66 mL 18.3 mL 36.6 mL
5 mM 0.73 mL 3.66 mL 7.32 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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