Nilotinib (AMN-107)

Catalog No.: A10644
Bcr-Abl inhibitor
Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM.
Grouped product items
Product Name Price Stock Qty
Nilotinib (AMN-107) 100mg
$30.00
In stock
Nilotinib (AMN-107) 200mg
$50.00
In stock
Nilotinib (AMN-107) 10mM * 1mL in DMSO
$72.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's Nilotinib (AMN-107) has been cited by 2 publications
  • Rami Shinnawi, .et al. , Stem Cell Reports, 2015, Oct 13; 5(4): 582-596 PMID: 26372632
  • Tetsuya Saita, .et al. , Biol Pharm Bull. , 2015, 38(10):1652-7 PMID: 26424026
  • Biological Activity
    Discription Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM.
    Targets
    Target Value
    Product Information
    Catalog Num A10644
    Formula C28H22F3N7O
    Molecular Weight 529.5
    CAS Number 641571-10-0
    SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 26 mg/mL (49.09 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 4% DMSO+30% PEG 300+5% Tween 80+ddH2O 2 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.89 mL 94.43 mL 188.86 mL
    0.5 mM 3.78 mL 18.89 mL 37.77 mL
    1 mM 1.89 mL 9.44 mL 18.89 mL
    5 mM 0.38 mL 1.89 mL 3.78 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy Nilotinib (AMN-107) | Nilotinib (AMN-107) Supplier | purchase Nilotinib (AMN-107) | Nilotinib (AMN-107) cost | Nilotinib (AMN-107) manufacturer | order Nilotinib (AMN-107) | Nilotinib (AMN-107) distributor | buy 641571-10-0 | 641571-10-0 Supplier | purchase 641571-10-0 | 641571-10-0 cost | 641571-10-0 manufacturer | order 641571-10-0 | 641571-10-0 distributor