Pimecrolimus

Catalog No.: A10732
Pimecrolimus is a natural ascomycin macrolactam that binds to macrophilin-12 (FKBP-12) and inhibits calcineurin as well as prolyl isomerase (rotamase).
Grouped product items
Product Name Price Stock Qty
Pimecrolimus 25mg
$40.00
In stock
Pimecrolimus 50mg
$72.00
In stock
Pimecrolimus 100mg
$130.00
In stock
Pimecrolimus 10mM * 1mL in DMSO
$55.00
In stock
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Biological Activity
Discription Pimecrolimus is a natural ascomycin macrolactam that binds to macrophilin-12 (FKBP-12) and inhibits calcineurin as well as prolyl isomerase (rotamase).
Product Information
Catalog Num A10732
Formula C43H68ClNO11
Molecular Weight 810.5
CAS Number 137071-32-0
SMILES CC[C@@H]1/C=C(\C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@@H]([C@@H](C4)OC)Cl)/C)O)C)OC)OC)C)/C
Synonyms Elidel, SDZ-ASM-981
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 94 mg/mL (115.98 mM)
Water Insoluble
Ethanol 94 mg/mL (115.98 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.34 mL 61.69 mL 123.38 mL
0.5 mM 2.47 mL 12.34 mL 24.68 mL
1 mM 1.23 mL 6.17 mL 12.34 mL
5 mM 0.25 mL 1.23 mL 2.47 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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