Thiamet G

Catalog No.: A12895
O-GlcNAcase inhibitor
Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal-hexosaminidase.
Grouped product items
Product Name Price Stock Qty
Thiamet G 5mg
$55.00
In stock
Thiamet G 10mg
$95.00
In stock
Thiamet G 25mg
$200.00
In stock
Thiamet G 50mg
$350.00
In stock
Thiamet G 10mM * 1mL in DMSO
$89.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Thiamet G has been cited by 3 publications
  • Kefan Wu, .et al. , Biomedicines, 2023, Apr 24;11(5):1259 PMID: 37238930
  • Wei Zhong Zhu, .et al. , PLoS One, 2022, Oct 26;17(10):e0276285 PMID: 36288343
  • Zhu WZ, .et al. , J Am Heart Assoc, 2019, Jun 4;8(11):e011260 PMID: 31131693
  • Biological Activity
    Discription Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal-hexosaminidase.
    Targets
    Target Value
    Product Information
    Catalog Num A12895
    Formula C9H16N2O4S
    Molecular Weight 248.3
    CAS Number 1009816-48-1
    SMILES CCNC1=NC2C(C(C(OC2S1)CO)O)O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 47 mg/mL (189.28 mM)
    Water 47 mg/mL (189.28 mM)
    Ethanol 11 mg/mL (44.29 mM)
    In vivo Saline 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 40.27 mL 201.37 mL 402.74 mL
    0.5 mM 8.05 mL 40.27 mL 80.55 mL
    1 mM 4.03 mL 20.14 mL 40.27 mL
    5 mM 0.81 mL 4.03 mL 8.05 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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