Fludarabine Phosphate (Fludara)

Catalog No.: A10395
Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.
Grouped product items
Product Name Price Stock Qty
Fludarabine Phosphate 10mg
$40.00
In stock
Fludarabine Phosphate 50mg
$120.00
In stock
Fludarabine Phosphate 100mg
$150.00
In stock
Fludarabine Phosphate 10mM * 1mL in DMSO
$60.00
In stock
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Biological Activity
Discription Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.
Targets
Target Value
Product Information
Catalog Num A10395
Formula C10H13FN5O7P
Molecular Weight 365.2
CAS Number 75607-67-9
SMILES O[C@H]1[C@H](O)[C@H](O[C@H]1n1cnc2c1nc(F)nc2N)COP(=O)(O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 66 mg/mL (180.71 mM)
Water Warmed: 2 mg/mL (5.47 mM)
Ethanol Insoluble
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.38 mL 136.91 mL 273.82 mL
0.5 mM 5.48 mL 27.38 mL 54.76 mL
1 mM 2.74 mL 13.69 mL 27.38 mL
5 mM 0.55 mL 2.74 mL 5.48 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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