Lonafarnib (SCH66336)

Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.
Grouped product items
Product Name Price Stock Qty
Lonafarnib (SCH66336) 5mg
$90.00
In stock
Lonafarnib (SCH66336) 10mg
$150.00
In stock
Lonafarnib (SCH66336) 25mg
$280.00
In stock
Lonafarnib (SCH66336) 50mg
$500.00
In stock
Lonafarnib (SCH66336) 10mM * 1mL in DMSO
$174.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's Lonafarnib (SCH66336) has been cited by 1 publications
  • Stella Liong, .et al. , Mediators Inflamm, 2018, 2018: 3645386 PMID: 30402038
  • Biological Activity
    Discription Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A12328
    Formula C27H31Br2ClN4O2
    Molecular Weight 638.82
    CAS Number 193275-84-2
    SMILES C1CN(CCC1CC(=O)N2CCC(CC2)[C@@H]3C4=C(C=C(C=C4CCC5=CC(=CN=C35)Br)Cl)Br)C(=O)N
    Synonyms Sarasar, SCH 66336, SCH66336, SCH-66336
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 116 mg/mL (181.58 mM)
    Water Insoluble
    Ethanol 116 mg/mL (181.58 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 15.65 mL 78.27 mL 156.54 mL
    0.5 mM 3.13 mL 15.65 mL 31.31 mL
    1 mM 1.57 mL 7.83 mL 15.65 mL
    5 mM 0.31 mL 1.57 mL 3.13 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy Lonafarnib (SCH66336) | Lonafarnib (SCH66336) Supplier | purchase Lonafarnib (SCH66336) | Lonafarnib (SCH66336) cost | Lonafarnib (SCH66336) manufacturer | order Lonafarnib (SCH66336) | Lonafarnib (SCH66336) distributor | buy 193275-84-2 | 193275-84-2 Supplier | purchase 193275-84-2 | 193275-84-2 cost | 193275-84-2 manufacturer | order 193275-84-2 | 193275-84-2 distributor