Reparixin

Catalog No.: A12383
CXCL8/CXCR1/2 Inhibitor
Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).
Grouped product items
Product Name Price Stock Qty
Reparixin 5mg
$135.00
In stock
Reparixin 10mg
$230.00
In stock
Reparixin 25mg
$405.00
In stock
Reparixin 100mg
$2,295.00
In stock
Bulk Size
Bulk Discount
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Reparixin has been cited by 2 publications
  • Naour AL, .et al. , J Mol Cell Biol, 2019, Sep 3 PMID: 31504643
  • Wigenstam E, .et al. , Toxicology, 2015, Feb 3;328:40-7 PMID: 25497111
  • Biological Activity
    Discription Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).
    Targets
    Target Value
    Product Information
    Catalog Num A12383
    Formula C14H21NO3S
    Molecular Weight 283.39
    CAS Number 266359-83-5
    SMILES C[C@H](C1=CC=C(C=C1)CC(C)C)C(=O)NS(=O)(=O)C
    Synonyms DF 1681Y; Repertaxin
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 52 mg/mL (183.49 mM)
    Water Insoluble
    Ethanol 52 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 35.29 mL 176.44 mL 352.87 mL
    0.5 mM 7.06 mL 35.29 mL 70.57 mL
    1 mM 3.53 mL 17.64 mL 35.29 mL
    5 mM 0.71 mL 3.53 mL 7.06 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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