OSI-930

Catalog No.: A10679
c-Kit/VEGFR Inhibitor
OSI-930 is a potent inhibitor of Kit, KDR, Flt, CSF-1R, c-Raf and Lck with IC50 of 80 nM, 9 nM, 8 nM, 15 nM, 41 nM and 22 nM, respectively.
Grouped product items
Product Name Price Stock Qty
OSI-930 5mg
$90.00
In stock
OSI-930 25mg
$200.00
In stock
OSI-930 50mg
$350.00
In stock
OSI-930 100mg
$600.00
In stock
OSI-930 10mM * 1mL in DMSO
$139.00
In stock
Bulk Size
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription OSI-930 is a potent inhibitor of Kit, KDR, Flt, CSF-1R, c-Raf and Lck with IC50 of 80 nM, 9 nM, 8 nM, 15 nM, 41 nM and 22 nM, respectively.
Targets
Target Value
Product Information
Catalog Num A10679
Formula C22H16F3N3O2S
Molecular Weight 443.4
CAS Number 728033-96-3
SMILES C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 85 mg/mL (191.68 mM)
Water Insoluble
Ethanol 3 mg/mL
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.55 mL 112.76 mL 225.53 mL
0.5 mM 4.51 mL 22.55 mL 45.11 mL
1 mM 2.26 mL 11.28 mL 22.55 mL
5 mM 0.45 mL 2.26 mL 4.51 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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