Biochanin A (4-Methylgenistein)

Catalog No.: A10146

Biochanin A is an antiproliferative and anti-inflammatory agent that inhibits iNOS expression and lipopolysacharide (LPS)-induced nitric oxide production in macrophages. Additionally, Biochanin A displays the ability to block phosphorylation of IκBα and p38 MAPK, which prevents NF-κB activation. Furthermore, Biochanin A has been observed to suppress IL-6, IL-1β, and TNF-α production.

Grouped product items
Product Name Price Stock Qty
Biochanin A 200mg
$50.00
In stock
Biochanin A 500mg
$80.00
In stock
Biochanin A 10mM * 1mL in DMSO
$50.00
In stock
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Biological Activity
Discription

Biochanin A is an antiproliferative and anti-inflammatory agent that inhibits iNOS expression and lipopolysacharide (LPS)-induced nitric oxide production in macrophages. Additionally, Biochanin A displays the ability to block phosphorylation of IκBα and p38 MAPK, which prevents NF-κB activation. Furthermore, Biochanin A has been observed to suppress IL-6, IL-1β, and TNF-α production.

Targets
Target Value
Product Information
Catalog Num A10146
Formula C16H12O5
Molecular Weight 284.3
CAS Number 491-80-5
SMILES COC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 51 mg/mL (179.41 mM)
Water Insoluble
Ethanol 8 mg/mL (28.14 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.17 mL 175.87 mL 351.74 mL
0.5 mM 7.03 mL 35.17 mL 70.35 mL
1 mM 3.52 mL 17.59 mL 35.17 mL
5 mM 0.7 mL 3.52 mL 7.03 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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