Indomethacin (Indocid, Indocin)

Indomethacin is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively. Indomethacin(Indocid, Indocin) is a non-steroidal anti-inflammatory compound commonly used to reduce fever, pain, stiffness, and swelling.
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Product Name Price Stock Qty
Indomethacin (Indocid, Indocin) 500mg
$45.00
In stock
Indomethacin 10mM * 1mL in DMSO
$61.00
In stock
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Adooq Products cited in reputable paper
Adooq's Indomethacin (Indocid, Indocin) has been cited by 3 publications
  • Reiko Watanabe, .et al. , J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
  • Azuma T, .et al. , Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
  • Azuma T, .et al. , Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347
  • Biological Activity
    Discription Indomethacin is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively. Indomethacin(Indocid, Indocin) is a non-steroidal anti-inflammatory compound commonly used to reduce fever, pain, stiffness, and swelling.
    Targets
    Target Value
    Product Information
    Catalog Num A10474
    Formula C19H16ClNO4
    Molecular Weight 357.79
    CAS Number 53-86-1
    SMILES CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O
    Synonyms Indomethacin, Indochron E-R, Indocin-SR, Indocid
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 63 mg/mL (176.08 mM)
    Water Insoluble
    Ethanol 21 mg/mL (58.69 mM)
    In vivo 5% DMSO+30% PEG 300+5% Tween 80+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.95 mL 139.75 mL 279.49 mL
    0.5 mM 5.59 mL 27.95 mL 55.9 mL
    1 mM 2.79 mL 13.97 mL 27.95 mL
    5 mM 0.56 mL 2.79 mL 5.59 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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