TPCA-1
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | TPCA-1 is a potent and selective inhibitor of human IκB kinase-2 (IKK-2) with IC50 = 17.9 nM for IKK-2 compared to 400nm for IKK-1. | ||
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Targets |
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Catalog Num | A11579 |
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Formula | C12H10FN3O2S |
Molecular Weight | 279.29 |
CAS Number | 507475-17-4 |
SMILES | C1=CC(=CC=C1C2=CC(=C(S2)NC(=O)N)C(=O)N)F |
Synonyms | TPCA1 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 49 mg/mL (175.44 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% Cremophor EL, 2% N,N-dimethylacetamide | 14 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 35.81 mL | 179.03 mL | 358.05 mL |
0.5 mM | 7.16 mL | 35.81 mL | 71.61 mL |
1 mM | 3.58 mL | 17.9 mL | 35.81 mL |
5 mM | 0.72 mL | 3.58 mL | 7.16 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2