NU6027

Catalog No.: A14136
ATR/CDK inhibitor
NU6027 is a potent inhibitor of cellular ATR activity (IC(50)=6.7 μM) and enhanced hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner.
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Product Name Stock
NU6027 10mg
NU6027 25mg
NU6027 50mg
NU6027 10mM * 1mL in DMSO
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Biological Activity
Discription NU6027 is a potent inhibitor of cellular ATR activity (IC(50)=6.7 μM) and enhanced hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner.
Targets
Target Value
Product Information
Catalog Num A14136
Formula C11H17N5O2
Molecular Weight 251.28
CAS Number 220036-08-8
SMILES C1CCC(CC1)COC2=NC(=NC(=C2N=O)N)N
Synonyms NU-6027, NU 6027
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 47 mg/mL (187.04 mM)
Water Insoluble
Ethanol 3 mg/mL (11.93 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 39.8 mL 198.98 mL 397.96 mL
0.5 mM 7.96 mL 39.8 mL 79.59 mL
1 mM 3.98 mL 19.9 mL 39.8 mL
5 mM 0.8 mL 3.98 mL 7.96 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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