UNC0646

Catalog No.: A13194
G9a/GLP HMTase inhibitor
UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50 values are 6 nM and 15 nM for G9a and GLP, respectively).
Grouped product items
Product Name Price Stock Qty
UNC0646 10mg
$100.00
In stock
UNC0646 25mg
$200.00
In stock
UNC0646 50mg
$350.00
In stock
UNC0646 100mg
$600.00
In stock
UNC0646 10mM * 1mL in DMSO
$80.00
In stock
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Biological Activity
Discription UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50 values are 6 nM and 15 nM for G9a and GLP, respectively).
Targets
Target Value
Product Information
Catalog Num A13194
Formula C36H59N7O2
Molecular Weight 621.9
CAS Number 1320288-17-2
SMILES CC(C)N1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C5CCCCC5)OC)OCCCN6CCCCC6
Synonyms UNC 0646, UNC-0646
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 31 mg/mL (49.84 mM)
Water Insoluble
Ethanol 47 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.08 mL 80.4 mL 160.8 mL
0.5 mM 3.22 mL 16.08 mL 32.16 mL
1 mM 1.61 mL 8.04 mL 16.08 mL
5 mM 0.32 mL 1.61 mL 3.22 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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