CVT-313

Catalog No.: A15054
CDK2 Inhibitor
CVT-313 is a potent, selective, reversible, and ATP-competitive inhibitor of CDK2 (IC50 = 0.5 uM for Cdk2/A and Cdk2/E; 4.2 uM for Cdk1/B; 215 uM for Cdk4/D1).
Grouped product items
Product Name Price Stock Qty
CVT-313 50mg
$380.00
In stock
CVT-313 200mg
$850.00
In stock
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Biological Activity
Discription CVT-313 is a potent, selective, reversible, and ATP-competitive inhibitor of CDK2 (IC50 = 0.5 uM for Cdk2/A and Cdk2/E; 4.2 uM for Cdk1/B; 215 uM for Cdk4/D1).
Targets
Target Value
Product Information
Catalog Num A15054
Formula C20H28N6O3
Molecular Weight 400.47
CAS Number 199986-75-9
SMILES CC(C)N1C=NC2=C1N=C(N=C2NCC3=CC=C(C=C3)OC)N(CCO)CCO
Synonyms CVT 313, NG 26, CVT313, NG26, NG-26
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 73 mg/mL (182.28 mM)
Water Insoluble
Ethanol 73 mg/mL (182.28 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.97 mL 124.85 mL 249.71 mL
0.5 mM 4.99 mL 24.97 mL 49.94 mL
1 mM 2.5 mL 12.49 mL 24.97 mL
5 mM 0.5 mL 2.5 mL 4.99 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

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This equation is commonly abbreviated as: C1V1 = C2V2

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