GLPG0634

Catalog No.: A13162
JAK1 inhibitor
GLPG0634 is an orally-available, selective inhibitor of JAK1 (Janus kinase 1) being developed by Galapagos for the treatment of rheumatoid arthritis and potentially other inflammatory diseases.
Grouped product items
Product Name Price Stock Qty
GLPG0634 5mg
$200.00
In stock
GLPG0634 10mg
$350.00
In stock
GLPG0634 25mg
$680.00
In stock
GLPG0634 50mg
$1,100.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's GLPG0634 has been cited by 1 publications
  • Keisuke Nishimura, .et al. , Arthritis Rheumatol., 2015, Apr;67(4):893-902 PMID: 25545152
  • Biological Activity
    Discription GLPG0634 is an orally-available, selective inhibitor of JAK1 (Janus kinase 1) being developed by Galapagos for the treatment of rheumatoid arthritis and potentially other inflammatory diseases.
    Targets
    Target Value
    Product Information
    Catalog Num A13162
    Formula C23H18N6O2
    Molecular Weight 410.15
    CAS Number 1206101-20-3
    SMILES c1cc(n2c(c1)nc(n2)NC(=O)C3CC3)c4ccc(cc4)OCc5ccc(nc5)C#N
    Synonyms GLPG 0634, GLPG-0634
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 0.09 mg/mL (0.22 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.38 mL 121.91 mL 243.81 mL
    0.5 mM 4.88 mL 24.38 mL 48.76 mL
    1 mM 2.44 mL 12.19 mL 24.38 mL
    5 mM 0.49 mL 2.44 mL 4.88 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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