PD168393

Catalog No.: A12725
EGFR inhibitor
PD168393 is a potent, cell-permeable, irreversible inhibitor of EGFR with IC50 value of 700 pM.
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Product Name Price Stock Qty
PD168393 5mg
$60.00
In stock
PD168393 10mg
$110.00
In stock
PD168393 50mg
$250.00
In stock
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Biological Activity
Discription PD168393 is a potent, cell-permeable, irreversible inhibitor of EGFR with IC50 value of 700 pM.
Targets
Target Value
Product Information
Catalog Num A12725
Formula C17H13BrN4O
Molecular Weight 369.22
CAS Number 194423-15-9
SMILES C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br
Synonyms PD-168393, PD 168393
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 72 mg/mL (195 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.08 mL 135.42 mL 270.84 mL
0.5 mM 5.42 mL 27.08 mL 54.17 mL
1 mM 2.71 mL 13.54 mL 27.08 mL
5 mM 0.54 mL 2.71 mL 5.42 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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