VGX-1027

Catalog No.: A12548
TLR4 Inhibitor
VGX-1027 displays immunomodulatory and anti-inflammatory activities by inhibiting toll-like receptor 4 (TLR4) signaling.
Grouped product items
Product Name Price Stock Qty
VGX-1027 5mg
$40.00
In stock
VGX-1027 10mg
$60.00
In stock
VGX-1027 25mg
$120.00
In stock
VGX-1027 50mg
$200.00
In stock
VGX-1027 10mM * 1mL in DMSO
$75.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription VGX-1027 displays immunomodulatory and anti-inflammatory activities by inhibiting toll-like receptor 4 (TLR4) signaling.
Targets
Target Value
Product Information
Catalog Num A12548
Formula C11H11NO3
Molecular Weight 205.21
CAS Number 6501-72-0
SMILES C1C(ON=C1C2=CC=CC=C2)CC(=O)O
Synonyms GIT 27, VGX1027, GIT27
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 38 mg/mL (185.17 mM)
Water Insoluble
Ethanol 38 mg/mL (185.17 mM)
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 48.73 mL 243.65 mL 487.31 mL
0.5 mM 9.75 mL 48.73 mL 97.46 mL
1 mM 4.87 mL 24.37 mL 48.73 mL
5 mM 0.97 mL 4.87 mL 9.75 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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