CC-930 (Tanzisertib)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | CC-930 is kinetically competitive with ATP in the JNK-dependent phosphorylation of the protein substrate c-Jun and potent against all isoforms of JNK (Ki(JNK1) = 44 ?? 3 nM, IC50(JNK1) = 61 nM, Ki(JNK2) = 6.2 ?? 0.6 nM, IC50(JNK2) = 5 nM, IC50(JNK3) = 5 nM) and selective against MAP kinases ERK1 and p38a with IC50 of 0.48 and 3.4 μM respectively | ||
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Targets |
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Catalog Num | A13564 |
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Formula | C21H23F3N6O2 |
Molecular Weight | 448.44 |
CAS Number | 899805-25-5 |
SMILES | C1COC[C@H]1N2C3=NC(=NC=C3N=C2NC4=C(C=C(C=C4F)F)F)NC5CCC(CC5)O |
Synonyms | Tanzisertib, CC 930, CC930 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 80 mg/mL (164.98 mM) | |
Water | Warmed: 4 mg/mL (8.24 mM) | ||
Ethanol | Warmed: 80 mg/mL (164.98 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.3 mL | 111.5 mL | 223 mL |
0.5 mM | 4.46 mL | 22.3 mL | 44.6 mL |
1 mM | 2.23 mL | 11.15 mL | 22.3 mL |
5 mM | 0.45 mL | 2.23 mL | 4.46 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2