6H05

Catalog No.: A16097
K-Ras inhibitor
6H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C).
Grouped product items
Product Name Price Stock Qty
6H05 5mg
$130.00
In stock
6H05 10mg
$240.00
In stock
6H05 50mg
$960.00
In stock
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Biological Activity
Discription 6H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C).
Product Information
Catalog Num A16097
Formula C20H30ClN3O2S3
Molecular Weight 476.12
CAS Number 1469338-01-9
SMILES CN(C)CCSSCCNC(=O)C1CCN(CC1)C(=O)CSC2=CC=C(C=C2)Cl
Synonyms K-Ras inhibitor
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 93 mg/mL (157.59 mM)
Water 93 mg/mL (157.59 mM)
Ethanol 93 mg/mL (157.59 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21 mL 105.02 mL 210.03 mL
0.5 mM 4.2 mL 21 mL 42.01 mL
1 mM 2.1 mL 10.5 mL 21 mL
5 mM 0.42 mL 2.1 mL 4.2 mL
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This equation is commonly abbreviated as: C1V1 = C2V2

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