NVP-TNKS656

Catalog No.: A15786
TNKS2 inhibitor
NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.
Grouped product items
Product Name Price Stock Qty
NVP-TNKS656 5mg
$230.00
In stock
NVP-TNKS656 10mg
$400.00
In stock
NVP-TNKS656 25mg
$690.00
In stock
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Biological Activity
Discription NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.
Targets
Target Value
Product Information
Catalog Num A15786
Formula C27H34N4O5
Molecular Weight 494.58
CAS Number 1419949-20-4
SMILES COC1=CC=C(C=C1)C(=O)C2CCN(CC2)CC(=O)N(CC3CC3)CC4=NC(=O)C5=C(N4)CCOC5
Synonyms TNKS656, TNKS-656
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 89 mg/mL (179.95 mM)
Water Insoluble
Ethanol Warmed: 9 mg/mL (18.19 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.22 mL 101.1 mL 202.19 mL
0.5 mM 4.04 mL 20.22 mL 40.44 mL
1 mM 2.02 mL 10.11 mL 20.22 mL
5 mM 0.4 mL 2.02 mL 4.04 mL
Useful Calculator

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