Altiratinib (DCC2701)

Catalog No.: A14387
c-Met/VEGFR inhibitor
Altiratinib is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro.
Grouped product items
Product Name Price Stock Qty
Altiratinib 5mg
$55.00
In stock
Altiratinib 10mg
$80.00
In stock
Altiratinib 25mg
$165.00
In stock
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Biological Activity
Discription Altiratinib is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro.
Targets
Target Value
Product Information
Catalog Num A14387
Formula C26H21F3N4O4
Molecular Weight 510.46
CAS Number 1345847-93-9
SMILES FC1=CC=C(NC(C2(C(NC3=C(F)C=C(OC4=CC(/N=C(O)/C5CC5)=NC=C4)C(F)=C3)=O)CC2)=O)C=C1
Synonyms DCC-2701, DCC2701, DCC 2701, DP 5164, DP5164, DP-5164
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 99 mg/mL (193.94 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.59 mL 97.95 mL 195.9 mL
0.5 mM 3.92 mL 19.59 mL 39.18 mL
1 mM 1.96 mL 9.8 mL 19.59 mL
5 mM 0.39 mL 1.96 mL 3.92 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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