AMG-8718

Catalog No.: A14407
BACE1 inhibitor
AMG-8718 is a potent and orally efficacious BACE1 inhibitor.
Grouped product items
Product Name Stock
AMG-8718 5mg
AMG-8718 10mg
AMG-8718 25mg
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Biological Activity
Discription AMG-8718 is a potent and orally efficacious BACE1 inhibitor.
Product Information
Catalog Num A14407
Formula C25H19FN4O3
Molecular Weight 442.44
CAS Number 1215868-94-2
SMILES NC(OC1)=N[C@@]21C3=CC(C4=CC=CN=C4F)=CC=C3OC5=NC=C(C#CC6(C)COC6)C=C52
Synonyms AMG 8718, AMG8718
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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