Gilteritinib (ASP2215)

Gilteritinib is a potent FLT3/AXL inhibitor, which showed potent antileukemic activity against AML with either or both FLT3-ITD and FLT3-D835 mutations.
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Product Name Price Stock Qty
Gilteritinib 5mg
$100.00
In stock
Gilteritinib 10mg
$150.00
In stock
Gilteritinib 25mg
$250.00
In stock
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Adooq Products cited in reputable paper
Adooq's Gilteritinib (ASP2215) has been cited by 1 publications
  • Mohammad Azhar, .et al. , Blood Adv, 2022, Aug 31 PMID: 36044389
  • Biological Activity
    Discription Gilteritinib is a potent FLT3/AXL inhibitor, which showed potent antileukemic activity against AML with either or both FLT3-ITD and FLT3-D835 mutations.
    Product Information
    Catalog Num A14411
    Formula C29H44N8O3
    Molecular Weight 552.71
    CAS Number 1254053-43-4
    SMILES CCC1=NC(=C(N=C1NC2CCOCC2)NC3=CC(=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC)C(=O)N
    Synonyms ASP2215, ASP-2215, ASP 2215
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 90 mg/mL (162.83 mM)
    Water Insoluble
    Ethanol 77 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.09 mL 90.46 mL 180.93 mL
    0.5 mM 3.62 mL 18.09 mL 36.19 mL
    1 mM 1.81 mL 9.05 mL 18.09 mL
    5 mM 0.36 mL 1.81 mL 3.62 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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