IM-12

Catalog No.: A14196
GSK-3β inhibitor
IM-12 is a cell-permeable indolylmaleimide that acts as a Glycogen synthase kinase 3β (GSK-3β) inhibitor, activating downstream components of canonical Wnt signaling.
Grouped product items
Product Name Price Stock Qty
IM-12 10mg
$60.00
In stock
IM-12 25mg
$120.00
In stock
IM-12 50mg
$200.00
In stock
IM-12 100mg
$350.00
In stock
IM-12 10mM * 1mL in DMSO
$82.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription IM-12 is a cell-permeable indolylmaleimide that acts as a Glycogen synthase kinase 3β (GSK-3β) inhibitor, activating downstream components of canonical Wnt signaling.
Targets
Target Value
Product Information
Catalog Num A14196
Formula C22H20FN3O2
Molecular Weight 377.41
CAS Number 1129669-05-1
SMILES CC1=C(C2=CC=CC=C2N1)C3=C(C(=O)N(C3=O)C)NCCC4=CC=C(C=C4)F
Synonyms IM12, IM 12
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 72 mg/mL (190.77 mM)
Water Insoluble
Ethanol Warmed: 10 mg/mL (26.49 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.5 mL 132.48 mL 264.96 mL
0.5 mM 5.3 mL 26.5 mL 52.99 mL
1 mM 2.65 mL 13.25 mL 26.5 mL
5 mM 0.53 mL 2.65 mL 5.3 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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