PX 12

Catalog No.: A13831
Trx-1 inhibitor
PX 12 inhibits hypoxia-induced HIF-1a transcriptional activity (IC50 11 nM) and proliferation of HT29 and MCF-7 tumor cells (IC50 1.9 and 0.9 uM, respectively).
Grouped product items
Product Name Price Stock Qty
PX 12 10mg
$85.00
In stock
PX 12 25mg
$160.00
In stock
PX 12 50mg
$300.00
In stock
PX 12 100mg
$500.00
In stock
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Biological Activity
Discription PX 12 inhibits hypoxia-induced HIF-1a transcriptional activity (IC50 11 nM) and proliferation of HT29 and MCF-7 tumor cells (IC50 1.9 and 0.9 uM, respectively).
Targets
Target Value
Product Information
Catalog Num A13831
Formula C7H12N2S2
Molecular Weight 188.31
CAS Number 141400-58-0
SMILES CCC(C)SSC1=NC=CN1
Synonyms IV-2, PX-12, PX12
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 37 mg/mL (196.48 mM)
Water Insoluble
Ethanol 37 mg/mL
In vivo 2% DMSO+30% PEG 300+ddH2O 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 53.1 mL 265.52 mL 531.04 mL
0.5 mM 10.62 mL 53.1 mL 106.21 mL
1 mM 5.31 mL 26.55 mL 53.1 mL
5 mM 1.06 mL 5.31 mL 10.62 mL
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