PJ 34 hydrochloride

PJ 34 hydrochloride is a potent inhibitor of poly(ADP-ribose) polymerase (PARP) (EC50 = 20 nM).
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Product Name Price Stock Qty
PJ 34 hydrochloride 10mg
$60.00
In stock
PJ 34 hydrochloride 25mg
$100.00
In stock
PJ 34 hydrochloride 50mg
$170.00
In stock
PJ 34 hydrochloride 100mg
$300.00
In stock
PJ 34 hydrochloride 10mM * 1mL in DMSO
$79.00
In stock
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Adooq Products cited in reputable paper
Adooq's PJ 34 hydrochloride has been cited by 2 publications
  • Wigle TJ, .et al. , SLAS Discov, 2019, Dec 19:2472555219883623 PMID: 31855104
  • Alvin Z.Lu, .et al. , Biochem Pharmacol, 2019, May 7. pii: S0006-2952(19)30171-6 PMID: 31075269
  • Biological Activity
    Discription PJ 34 hydrochloride is a potent inhibitor of poly(ADP-ribose) polymerase (PARP) (EC50 = 20 nM).
    Targets
    Target Value
    Product Information
    Catalog Num A12665
    Formula C17H17N3O2.HCl
    Molecular Weight 331.8
    CAS Number 344458-15-7
    SMILES CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.Cl
    Synonyms PJ34, PJ-34
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 57 mg/mL (171.79 mM)
    Water 57 mg/mL (171.79 mM)
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 14 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 30.14 mL 150.69 mL 301.39 mL
    0.5 mM 6.03 mL 30.14 mL 60.28 mL
    1 mM 3.01 mL 15.07 mL 30.14 mL
    5 mM 0.6 mL 3.01 mL 6.03 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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