(+)-Apogossypol

Catalog No.: A16316
Bcl-2 family inhibitor
(+)-Apogossypol is a potent inhibitor of Bcl-2 family proteins; competing with the BH3 peptide-binding sites on Bcl-2, Bcl-XL, Mcl-1, Bcl-W, and Bcl-B, but not Bfl-1, with IC50s of 0.5 to 2 μM.
Grouped product items
Product Name Price Stock Qty
(+)-Apogossypol 5mg
$320.00
In stock
(+)-Apogossypol 10mg
$580.00
In stock
(+)-Apogossypol 50mg
$1,600.00
In stock
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Biological Activity
Discription (+)-Apogossypol is a potent inhibitor of Bcl-2 family proteins; competing with the BH3 peptide-binding sites on Bcl-2, Bcl-XL, Mcl-1, Bcl-W, and Bcl-B, but not Bfl-1, with IC50s of 0.5 to 2 μM.
Targets
Target Value
Product Information
Catalog Num A16316
Formula C28H30O6
Molecular Weight 462.53
CAS Number 66389-74-0
SMILES CC(C=C1C(C(C)C)=C(O)C(O)=CC1=C2O)=[C@]2[C@@]3=C(C)C=C4C(C=C(O)C(O)=C4C(C)C)=C3O
Synonyms Apogossypol, NSC736630
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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