Ro 61-8048

Catalog No.: A12833
Hydroxylase Inhibitor
Ro 61-8048 is a potent and competitive kynurenine 3-hydroxylase inhibitor (Ki = 4.8 nM, IC50 = 37 nM).
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Product Name Price Stock Qty
Ro 61-8048 10mg
$70.00
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Ro 61-8048 25mg
$130.00
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Ro 61-8048 50mg
$200.00
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Ro 61-8048 100mg
$320.00
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Adooq Products cited in reputable paper
Adooq's Ro 61-8048 has been cited by 1 publications
  • Tianxing Ying, .et al. , Cancers (Basel), 2022, Dec 30;15(1):243 PMID: 36612238
  • Biological Activity
    Discription Ro 61-8048 is a potent and competitive kynurenine 3-hydroxylase inhibitor (Ki = 4.8 nM, IC50 = 37 nM).
    Targets
    Target Value
    Product Information
    Catalog Num A12833
    Formula C17H15N3O6S2
    Molecular Weight 421.45
    CAS Number 199666-03-0
    SMILES COC1=C(C=C(C=C1)S(=O)(=O)NC2=NC(=CS2)C3=CC(=CC=C3)[N+](=O)[O-])OC
    Synonyms Ro61-8048
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 80 mg/mL (189.82 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.73 mL 118.64 mL 237.28 mL
    0.5 mM 4.75 mL 23.73 mL 47.46 mL
    1 mM 2.37 mL 11.86 mL 23.73 mL
    5 mM 0.47 mL 2.37 mL 4.75 mL
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    This equation is commonly abbreviated as: C1V1 = C2V2

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